This site is intended only for Australian Healthcare Professionals
Menu
Close
Menu
Close
A 1-year, double-blind, triple-dummy, phase 3b/4, active comparator, head-to-head controlled trial in which 1146 patients with moderately to severely active RA who had an inadequate response to MTX received XELJANZ 5 mg BID, XELJANZ 5 mg BID + MTX, or Humira® 40 mg SC q 2 wk + MTX. The primary endpoint was ACR50 at month 6 powered to test noninferiority through independent comparisons of XELJANZ 5 mg BID to Humira® 40 mg SC q 2 wk + MTX; XELJANZ 5 mg BID + MTX to Humira® 40 mg SC q 2 wk + MTX; and XELJANZ 5 mg BID to XELJANZ 5 mg BID + MTX.1,3
Learn more about the XELJANZ safety profile
Learn about dosing with XELJANZ, the first oral JAKi approved for RA
Find out more about the JAKi with the longest market experience in RA, PsA, UC, AS and JIA
▼This medicinal product is subject to additional monitoring in Australia. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse events at www.tga.gov.au/reporting-problems.
WARNINGS XELJANZ should only be used if no suitable treatment alternatives are available in patients:
See PI for details, Section 4.4 Special Warnings and Precautions for Use: Mortality; Major Adverse Cardiovascular Events (including Myocardial Infarction); Thrombosis; Malignancy and Lymphoproliferative Disorder (excluding Nonmelanoma Skin Cancer [NMSC]); Skin Cancer and Use in the Elderly. |
Before prescribing, please review full Product Information available here.
PBS Information: Authority required. Refer to PBS Schedule for full authority information.
®Registered Trademark.
PP-XEL-AUS-1403 10/23.
To access further materials, resources and receive communication about Pfizer medicines and vaccines.
The site is intended for Australian healthcare professionals.
©2023 Pfizer Australia Pty Ltd. Sydney, Australia. All rights reserved.
PP-UNP-AUS-0551 12/23.