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The below information is not exhaustive. For a comprehensive list of considerations, please refer to the approved Product Information.
Laboratory monitoring recommendations for patients taking XELJANZ®
Dose adjustment or interruption is recommended for management of lymphopenia, neutropenia, and anaemia. If lymphocyte count or absolute neutrophil count is <0.5 x 109 cells/L, XELJANZ should be discontinued1
Treatment with XELJANZ should be interrupted in patients who develop Hb levels <80 g/L or those whose Hb levels drop >20 g/L on treatment1
Avoid initiation of XELJANZ treatment in patients with1:
Learn more about the XELJANZ safety profile
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▼This medicinal product is subject to additional monitoring in Australia. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse events at www.tga.gov.au/reporting-problems.
XELJANZ should only be used if no suitable treatment alternatives are available in patients:
See PI for details, Section 4.4 Special Warnings and Precautions for Use: Mortality; Major Adverse Cardiovascular Events (including Myocardial Infarction); Thrombosis; Malignancy and Lymphoproliferative Disorder (excluding Nonmelanoma Skin Cancer [NMSC]); Skin Cancer and Use in the Elderly.
Before prescribing, please review full Product Information available here.
PBS Information: Authority required for the treatment of adults with severe active rheumatoid arthritis and for adults with severe psoriatic arthritis and for adults with moderate-to-severe ulcerative colitis. Refer to the PBS Schedule for full authority information. This product is not listed on the PBS for juvenile idiopathic arthritis, juvenile psoriatic arthritis, or ankylosing spondylitis.
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